Reasons why COVID-19 vaccines may not grant lifetime immunity like other vaccines

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Not only do COVID-19 vaccines do a ‘good enough’ job, it is also important to establish that no two vaccines or pathogens are the same and that the immune defenses they generate cannot be adequately compared. For one thing, the threshold of protection, or the immunity needed to keep a person from getting sick, differs greatly for each pathogen and the severity of the infection it might cause. For this reason, it could be considered possible that COVID-19 vaccines generate a comparatively less durable or diminishing response.

It could also mean that we have to wait longer to get the ‘ideal’ results we want from our COVID-19 vaccines. In addition, it should also be noted that the magnitude of antibodies and immune responses seen with other vaccines differ in counts. If the measles vaccine builds up antibodies for life, the tetanus vaccine may have spoiling antibodies, which, however, are offset by the large number of antibodies created in the first place. These vaccines have also gone through years and years of progress and research to help track antibody declines and provide updates when needed, which is not possible at this time with COVID-19.



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